大泡性角膜病变系指角膜上皮及基质层长期水肿,致使上皮和上皮下形成大小不等的水泡,并且水泡多在同一部位反复发生和破溃,基质水肿增厚,新生血管伸入。它可由多种眼病引起,也是一些内眼手术后的并发症之一。这种病变使患眼视力低下,磨痛,异物感、畏光、流泪等刺激症状很重,当水泡破溃时还伴有难以忍受的剧痛。目前对该病治疗甚感困难,许多患者由于长期痛苦难忍,不得不摘除眼球。 Bullous keratopathy refers to the long-term edema of the corneal epithelium and stroma, resulting in the formation of epithelial and epithelial cells of varying sizes blisters, and blisters in the same place repeatedly and ulceration, stromal edema thickening, neovascular extension. It can be caused by a variety of eye diseases, but also one of the complications of some eye surgery. This lesion makes the eyesight low, grinding, foreign body sensation, photophobia, tearing and other irritating symptoms are heavy, when the blisters rupture accompanied by unbearable pain. Currently the treatment of the disease is very difficult, many patients had long-term painful, had to remove the eye.