在流行性病学的统计中,肺、口腔、舌、唇、喉头、食管癌都可能与吸烟有关。但长期以来,吸烟引起这些癌症的原理还不明确。本文应用近年来发展起来的测定诱变剂——致癌剂细胞遗传学方法,小白鼠骨髓嗜多染红细胞微核技术,对香烟烟雾凝聚物进行活体测定,试图从染色体断裂效应角度证实香烟烟雾凝聚物的诱变性及致癌性。 In epidemiological statistics, lung, mouth, tongue, lips, throat, and esophageal cancer may all be associated with smoking. But for a long time, the principle of smoking caused these cancers is still not clear. In this paper, the mutagenic agent-carcinogen cytogenetic method developed in recent years and the micronucleus technique of polychromatic erythroblasts in bone marrow of mice have been used to carry out the in vivo measurement of cigarette smoke agglutination, attempting to confirm the condensation of cigarette smoke from the perspective of chromosome breakage effect. Mutagenicity and carcinogenicity.