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目的观察急性心肌梗死血清甲状腺激素变化 ,并探讨其临床意义。方法急性心肌梗死发病 2 4小时内入院患者 40例 ,分别于入院次日测定肌酸磷酸激酶 ,入院第 2、3日及第 9、1 0日测定血清 FT3、FT4、r T3。结果 1入院次日肌酸磷酸激酶与入院第 2、3天 FT3、r T3无明显相关关系 ,而与 FT4呈显著负相关 ;2与对照组比较 ,AMI组第 2、3天 FT3显著下降 ,r T3显著增高 ,FT4无明显差异 ,第 9、1 0天仅 r T3显著增高 ,FT3、FT4无显著差异 ;3入院第 2、3天 ,大范围梗死组与小范围梗死组比较及泵功能 、 级组与 、 级组比较 ,其 FT3、FT4均显著下降 ,r T3显著升高。结论急性心肌梗死时肌酸磷酸激酶与 FT3、r T3无明显相关关系 ,与 FT4呈显著负相关 ;急性心肌梗死时 FT3显著下降 ,r T3显著升高 ,梗死范围越大或泵功能越差这种变化越显著 ,并出现 FT4显著下降
Objective To observe the changes of serum thyroid hormone in patients with acute myocardial infarction and to explore its clinical significance. Methods Forty patients admitted to hospital within 24 hours after acute myocardial infarction were enrolled. Creatine phosphokinase was measured on the next day after admission. Serum FT3, FT4 and r T3 were measured on the 2nd, 3rd, and 9th day after admission. Results 1 On the second day of hospital admission, creatine phosphokinase had no significant correlation with FT3 and T3 on the 2nd and 3rd days after admission, but negatively correlated with FT4.2 Compared with the control group, FT3 decreased significantly on the 2nd and 3rd days in the AMI group, r T3 significantly increased, FT4 no significant difference in the 9,10 days only r T3 was significantly increased, FT3, FT4 no significant difference; 3 admission days 2,3 days, large infarct group and small infarction group and pump function The level of FT3 and FT4 in grade group and grade group were significantly decreased, while r T3 was significantly increased. Conclusions Creatine phosphokinase in acute myocardial infarction has no significant correlation with FT3 and T3, and has a significant negative correlation with FT4. FT3 significantly decreases and r T3 increases significantly in acute myocardial infarction. The larger the infarct size or the worse the pump function The more significant the changes were, and a significant decrease in FT4 occurred