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为了解深圳市检出脊髓灰质炎 (脊灰 )疫苗株病毒的急性弛缓性麻痹 (AFP)病例流行病学特征及疫苗相关麻痹型脊灰 (VAPP)病例发生情况 ,对 1 994~ 2 0 0 1年检出脊灰疫苗株病毒的AFP病例进行分析。结果显示 :病例分布在 0~ 3岁儿童 ,男性多于女性 ;发病时间、地区无明显聚集趋势 ;无脊灰疫苗免疫史的占 55 .55 % ,均为外来流动儿童 ;检出脊灰疫苗株Ⅱ型病毒占 44 .45 % ,残留麻痹率高。VAPP发生率为 0 .90 / 1 0 0万 ,服苗者VAPP发生率为0 .68/ 1 0 0万 ,首次服苗VAPP发生率为 4 .0 9/ 1 0 0万 ,服苗接触者VAPP发生率为 0 .2 3/ 1 0 0万。提示应加强外环境中脊灰病毒的监测和相关研究
In order to understand the epidemiological characteristics of acute flaccid paralysis (AFP) cases and the incidence of vaccine-associated paralytic poliovirus (VAPP) cases of poliovirus (polio) vaccine strains detected in Shenzhen, One year of detection of AFP cases of poliovirus was analyzed. The results showed that: the cases were distributed in children aged 0-3 years, more men than women; onset time, the region no significant aggregation trend; polio vaccine-free history accounted for 55.55%, all migrant children; detected polio vaccine Strain type II virus accounted for 44.45%, residual paralysis rate. The incidence of VAPP was 0.090 / 100 million, the incidence of VAPP was 0.68 / 100 million for the first time, the incidence rate of VAPP was 4.90% The incidence of VAPP was 0.231 / 10 million. It is suggested that poliovirus surveillance and related research should be strengthened in the external environment