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目的:探究并分析持续缓慢低效血液透析患者应用枸橼酸钠抗凝的护理作用。方法:选取2010年5月至2015年5月我院收治的急慢性肾功能不全需透析维持的患者237例。透析时间最短8天(放弃治疗),最长10年1个月,均数2年2个月,中位数2年7个月。综合参考年龄性别等因素将其分为两组,A组:肝素抗凝组,B组:枸橼酸钠抗凝组。两组受试者均在透析维持过程时给予相应处理,观察各处理组透析过程中各类并发症的发生率。结果:A组对于各类并发症的总发生率为35%,明显高于其余B组(p<0.05),具有统计学意义。结论:持续缓慢低效血液透析患者应用枸橼酸钠抗凝,可以显著减少透析过程中导管相关出血、导管相关感染、导管功能异常等并发症的总发生率,临床上值得推广应用。
Objective: To explore and analyze the nursing effect of sodium citrate anticoagulation in patients with sustained slow and inefficient hemodialysis. Methods: From May 2010 to May 2015 in our hospital admitted to our hospital for dialysis to maintain acute and chronic renal insufficiency in 237 patients. The shortest dialysis time of 8 days (to give up treatment), up to 10 years and 1 month, mean 2 years and 2 months, the median 2 years and 7 months. According to the age and sex, the patients were divided into two groups: A group: heparin anticoagulation group, B group: sodium citrate anticoagulation group. The two groups of subjects were given corresponding treatment during the course of dialysis maintenance, and observed the incidence of various complications during dialysis in each treatment group. Results: The total incidence of various complications in group A was 35%, which was significantly higher than that in the remaining group B (p <0.05), which was statistically significant. Conclusion: The application of sodium citrate anticoagulation in patients with sustained slow inefficient hemodialysis can significantly reduce the incidence of catheter-related hemorrhage, catheter-related infections, catheter dysfunction and other complications during dialysis, which is worth popularizing in clinic.