严重颅脑损伤常引起呼吸功能障碍 ,甚至发展成为急性呼吸窘迫综合征(ARDS)。创伤和感染是ARDS发病的主要原因 ,两者还可以互相促进。近年来已越来越重视对发生ARDS前期的研究。动物模型在研究ARDS早期的发病机制、临床表现、病理生理、血气变化和治疗等方面起到了重要作用。用? Severe craniocerebral injury often leads to respiratory dysfunction, and even developed into acute respiratory distress syndrome (ARDS). Trauma and infection are the main causes of ARDS, and the two can promote each other. In recent years, more and more emphasis on the occurrence of pre-ARDS research. Animal models play an important role in studying the early pathogenesis, clinical manifestations, pathophysiology, blood gas changes and treatment of ARDS. use?