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目的:观察甘草酸铋散、克拉霉素、左氧氟沙星治疗幽门螺杆菌消化道溃疡的疗效。方法:40例幽门螺杆菌性消化道溃疡患者随机平分为两组各20例,治疗组给予甘草酸铋散、克拉霉素、左氧氟沙星联合治疗,对照组给予埃索美拉唑镁、克拉霉素、左氧氟沙星联合治疗。结果:经过治疗后,治疗组总有效率95.0%,对照组65.0%,说明治疗组临床综合疗效明显优于对照组(P<0.05)。治疗前临床症状评分对比无显著性差异,经治疗后都有明显下降(P<0.05),但是治疗组下降幅度明显高于对照组(P<0.05)。结论:甘草酸铋散、克拉霉素、左氧氟沙星治疗幽门螺杆菌消化道溃疡疗效好,可更有效地改善临床症状。
Objective: To observe the curative effect of Helicobacter pylori peptic ulcer treated with bismuth licorice powder, clarithromycin and levofloxacin. Methods: Forty patients with Helicobacter pylori ulcer were randomly divided into two groups (n = 20 in each group). The treatment group was treated with combination of bixivium glycyrrhizinate, clarithromycin and levofloxacin, the control group was given esomeprazole magnesium, clarithromycin , Levofloxacin combination therapy. Results: After treatment, the total effective rate was 95.0% in the treatment group and 65.0% in the control group, indicating that the comprehensive clinical efficacy of the treatment group was significantly better than that of the control group (P <0.05). There was no significant difference in scores of clinical symptoms before treatment, but after treatment, they both decreased significantly (P <0.05), but the decrease in treatment group was significantly higher than that in control group (P <0.05). Conclusion: Bixi powder glycyrrhizin, clarithromycin, levofloxacin treatment of Helicobacter pylori peptic ulcer good effect, can be more effective in improving clinical symptoms.