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为研究低钙动物的生长代谢及与疾病的关系。介绍一种可行的不同血钙水平大鼠动物模型，通过控制膳食内钙水平对所饲大鼠血钙进行调节。用Ｗｉｓｔａｒ大鼠，按体重和性别均匀分层分为７组。所用的基础ＬＣ饲料，是以玉米面为主的膳食配方所配成，其中低钙特点突出，所饲大鼠血钙水平明显低下，体重生长迟缓、代谢偏低。研究结果表明，ＬＣ组大鼠血清Ｃａ水平仅及Ｓｔｏｃｋ组一半，体重增长迟缓，当膳食补Ｃａ后，血Ｃａ水平随补Ｃａ量逐渐升高，而体重增长也随之变化升高，呈明显的量效关系，ＬＣ＋６００Ｃａ组血Ｃａ接近正常水平。当膳食内总钙在１０００ｍｇ／ｋｇ时，即ＬＣ＋６００ｍｇ／ｋｇ组，上述生长迟缓的状态即被改善，Ｐ＜００１。
In order to study the growth and metabolism of low-calcium animals and the relationship with the disease. A feasible animal model of different calcium levels in rats was introduced to regulate the blood calcium in rats by controlling the level of dietary calcium. Wistar rats were evenly divided into 7 groups according to body weight and sex. The basic LC feed used is based on cornmeal-based diet formula, in which low-calcium characteristics are prominent, the level of serum calcium is significantly lower in rats, body weight growth retardation and low metabolism. The results showed that the level of serum Ca in LC group was only half of that in Stock group, and the weight gain was slow. When the dietary supplement of calcium, the level of Ca in serum increased gradually with the supplement of Ca and the change of body weight increased obviously Dose-effect relationship, LC + 600Ca blood Ca close to normal levels. When the total dietary calcium at 1000mg / kg, that LC + 600mg / kg group, the above state of retardation is improved, P <0 01.