肝性脑病是肝硬化的常见并发症,氨中毒学说在其发病机制中占有重要地位,幽门螺杆菌因富含尿素酶可迅速分解尿素而产生氨,故可能与肝性脑病的发生密切相关。其与肝硬化高氨血症之间的关系日益受到重视,本文对此做一综述。 Hepatic encephalopathy is a common complication of cirrhosis. The theory of ammonia poisoning plays an important role in its pathogenesis. Helicobacter pylori, which is rich in urease, can rapidly decompose urea and produce ammonia, so it may be closely related to the occurrence of hepatic encephalopathy. Its relationship with cirrhosis and hyperammonemia is paid more and more attention. This article reviews this issue.