目的分析性激素检验不孕症的临床诊断效果。方法随机选取2015年3月—2016年11月收治的48例女性不孕症患者,将其设为研究组;选取同期参与体检的48名女性健康者作为对照组。检测研究组和对照组的性激素水平包括催乳素(PRL)、卵泡刺激素(FSH)、孕酮(P)、雌二醇(E2)、黄体生成素(LH)以及睾酮(T),并采用t检验分析,以P<0.05为差异有统计学意义。结果研究组的PRL、P和T水平分别为(431.5±132.9)ng/ml、(2.1±1.8)ng/ml、(0.9±0.3)ng/ml显著高于对照组(319.2±103.5)ng/ml、(1.5±0.7)ng/ml、(0.5±0.2)ng/ml,差异有统计学意义(均P<0.05);而研究组的FSH和E2水平[(4.1±1.9)m IU/ml、(38.5±31.5)pg/ml]则显著低于对照组[(6.7±2.1)m IU/ml、(69.3±41.9)pg/ml],差异有统计学意义(均P<0.05);研究组LH水平[(4.4±3.1)m IU/ml]与对照组[(4.3±3.0)m IU/ml]比较,差异无统计学意义(P>0.05)。结论不孕症诊断过程中,通过检验性激素水平,掌握PRL、FSH、P、E2和T水平,可为临床诊断提供指导作用。 Objective To analyze the clinical diagnosis of infertility by sex hormones. Methods Forty-eight female infertility patients who were admitted to our hospital from March 2015 to November 2016 were selected as study group. Forty-eight female healthy subjects participated in the physical examination at the same period as the control group. Sex hormones in the study and control groups included prolactin (PRL), follicle stimulating hormone (FSH), progesterone (P), estradiol (E2), luteinizing hormone (LH) and testosterone (T) t test analysis, P <0.05 was considered statistically significant. Results The levels of PRL, P and T in the study group were significantly higher than those in the control group (431.5 ± 132.9 ng / ml, 2.1 ± 1.8 ng / ml, 0.9 ± 0.3 ng / ml vs 319.2 ± 103.5 ng / ml, (1.5 ± 0.7) ng / ml and (0.5 ± 0.2) ng / ml respectively (all P <0.05), while the levels of FSH and E2 in the study group were (4.1 ± 1.9) mIU / ml , (38.5 ± 31.5) pg / ml] was significantly lower than that of the control group [(6.7 ± 2.1) m IU / ml, (69.3 ± 41.9) pg / ml] There was no significant difference in LH level between the two groups ([(4.4 ± 3.1) m IU / ml] and control group [(4.3 ± 3.0) m IU / ml] Conclusions In the process of infertility diagnosis, the level of PRL, FSH, P, E2 and T can be mastered by examining sex hormone levels, which may provide guidance for clinical diagnosis.