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目的探讨我院喹诺酮类药物的应用现状及趋势。方法采用限定日剂量方法，对我院2009～2011年喹诺酮类药物的应用品种、销售金额、用药频度（DDDs）和日均费用（DDC）进行统计、分析。结果3年来，在口服喹诺酮类药物中，销售金额处于前三位的是加替沙星胶囊、左氧氟沙星胶囊、氟罗沙星胶囊；在注射喹诺酮类药物中，销售金额和DDDs排序列前四位的有盐酸左氧氟沙星注射液、加替沙星针、氟罗沙星针、依诺沙星注射液。结论我院喹诺酮类药物应用基本合理，但仍应进一步加强其使用监督管理。“,” Objective To evaluate the utilization and tendency of quinolones in our hospital. Methods Using DDD meth-od, the utilization of quinolones in our hospital from 2009 to 2011 were analyzed statistical y in terms of drug variety, consump-tion sum, DDDs and DDC, etc. Results The percentages of the consumption sum of quinolone in antibiotic drugs decreased year by year. Over the 3 years, the first 3 quinolones oral agents in the list of consumption sum and DDDs were Gatifloxacin capsules, Levofloxacin capsules and Fleroxacin capsules.The first 4 quinolones for injection in the list of consumption sum and DDDs included Levofloxacin injection, Gatifloxacin injection, Fleroxacin injection, Enoxacin injection. Conclusion The application of quinolone in our hospital is reasonable but should be strengthened in respect of the management of drug use.