目的改进血竭药材检验标准中血竭素高氯酸盐的含量测定方法。方法提取溶剂改为5%磷酸甲醇溶液,提取方法修订为“超声提取10 min后静置4 h”。结果血竭素含量测定结果稳定,测定值有较大提高。结论该方法操作简便、快捷,能有效地改善血竭药材含量测定中测定数据不稳定、重现性差的情况。 Objective To improve the determination of blood DRG perchlorate content of the test method. Methods The extraction solvent was changed to 5% phosphoric acid methanol solution. The extraction method was revised to “Ultrasonic extraction for 10 min and then allowed to stand for 4 h”. Results Results determination of dracorhodin stable, measured values ​​have greatly improved. Conclusion The method is simple, rapid, and can effectively improve the determination of blood drug content determination of unstable, poor reproducibility of the situation.