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类风湿关节炎(简称类风湿,RA)是一自身免疫疾病,最重要的病理改变是滑膜炎,但也可侵及浆膜、心、肺及眼等器官。本文采用免疫组织化学方法对RA及其它风湿性疾病的滑膜进行了检测,探讨了此项检查在RA诊断中的意义。材料与方法一、病例的选择 46例各种关节病患者滑膜标本取自北京协和医院内科及北京建筑工人医院骨科,均为住院并施行关节镜手术的病人,术后诊断为:RA21例,男7例、女14例,年龄 17～63岁。病程最短者1年,最长者18年,平均6.5年左右;血清阴性脊柱关节病4例,反应性关节炎4例;不明原因滑膜炎4
Rheumatoid arthritis (RA) is an autoimmune disease. The most important pathological change is synovitis, but it can also invade organs such as serosa, heart, lungs and eyes. In this paper, we used immunohistochemistry to detect the synovium of RA and other rheumatic diseases and explored the significance of this test in the diagnosis of RA. Materials and methods First, the choice of cases 46 cases of various types of synovial synovial specimens from the Peking Union Medical College Hospital and Beijing Construction Workers Hospital Orthopedics, are hospitalized and patients underwent arthroscopic surgery, postoperative diagnosis: RA21 cases, 7 males and 14 females, aged 17 to 63 years old. The shortest duration of 1 year, the longest 18 years, an average of 6.5 years; seronegative spondyloarthropathy in 4 cases, 4 cases of reactive arthritis; unexplained synovitis 4