近三年内已有报道从10余种人体恶性肿瘤应用DNA转染和分子生物学技术鉴定和分离癌基因,例如从膀胱癌、肺癌分离出Ha-ras;从肺癌、结肠癌、胆囊癌、胰腺癌卵巢癌、某些软组织肉瘤中分离出Ki-ras;从纤维肉瘤、横纹肌肉瘤、神经母细胞瘤、髓细胞性白血病和T细胞淋巴瘤等分离出N-ras等。但关于我国常见的原发性肝癌的转化基因尚未见正式报道。本文描述从原发性肝癌、肝癌7402细 In the past three years, there have been reports of the identification and isolation of oncogenes from more than 10 human malignancies using DNA transfection and molecular biology techniques, such as the isolation of Ha-ras from bladder cancer and lung cancer; from lung cancer, colon cancer, gallbladder cancer, and pancreas Ki-ras has been isolated from ovarian cancer and certain soft tissue sarcomas. N-ras has been isolated from fibrosarcoma, rhabdomyosarcoma, neuroblastoma, myeloid leukemia and T-cell lymphoma. However, there has not been any official report on the transformation genes of common liver cancer in China. This article describes from the primary liver cancer, liver cancer 7402