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引言 1969年,Rygaard和Povlsen二氏报告,他们异种移植人的结肠癌于裸体小鼠(Nude Mice)获得成功.从那时起,不少实验室证实,人体不同部位的肿瘤都可在裸体小鼠体内生长.多数报告是取人类的黑色素瘤、结肠腺癌和恶性淋巴瘤的组织直接做异种移植(Sordat氏等,1974年;Epstein氏等,1976年;Povlsen和Rygaard二氏,1976年),或者取已先在组织培养室中建株的细胞做异种移植(Giovanella氏等,1974年;Fogh氏等,1977年).只有一小部分工作是移植特殊类型的肿瘤.至于肺脏、骨骼、软组织和泌尿生殖
INTRODUCTION In 1969, Rygaard and Povlsen II reported that their xenotransplanted human colon cancer was successful in nude mice (Nude Mice). Since then, many laboratories have confirmed that tumors in different parts of the body can be found in nude mice. In vivo growth in mice. Most reports are taken directly from xenografts of human melanoma, colon adenocarcinoma, and malignant lymphoma tissues (Sordat et al., 1974; Epstein et al., 1976; Povlsen and Rygaard II, 1976). Or, cells that have previously been constructed in a tissue culture room may be used for xenotransplantation (Giovanella et al., 1974; Fogh et al., 1977). Only a small portion of the work involves transplanting special types of tumors. As for lungs, bones, Soft tissue and urogenital