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[Objective] This study to investigate the inhibitory effects of mycelium polysaccharide from Ganoderma lucidum Karst and Cordyceps sobolifera (Hill)Berk. et Br. on mouse Lewis lung cancer. [Method] For each healthy rat tested, 0.2 ml of lung cancer suspension was inoculated at the axilla. The rats were medicated with mycelium polysaccharides from G. lucidum and C. sobolifera for continuous 9 d by intragastric administration for measuring the indices of thymus and spleen and the tumor inhibition rate, thus establishing the lung cancer suspension model. [Result] At the dose of 200 mg/kg·d, both G. lucidum and C. sobolifera reached the optimal inhibition rates, of 50.2% and 46.3% respectively. [Conclusion] Mycelium polysaccharides from G. lucidum and C. sobolifera are endowed with inhibitory effects on Lewis lung cancer, and the former one is superior to the latter.
[Objective] This study to investigate the inhibitory effects of mycelium polysaccharide from Ganoderma lucidum Karst and Cordyceps sobolifera (Hill) Berk. Et Br. On mouse Lewis lung cancer. [Method] For each healthy rat tested, 0.2 ml of lung cancer suspension was inoculated at the axilla. The rats were medicated with mycelium polysaccharides from G. lucidum and C. sobolifera for continuous 9 d by intragastric administration for measuring the indices of thymus and spleen and the tumor inhibition rate, thus establishing the lung cancer suspension model. [ Results] At the dose of 200 mg / kg · d, both G. lucidum and C. sobolifera reached the optimal inhibition rates, of 50.2% and 46.3% respectively. [Conclusion] Mycelium polysaccharides from G. lucidum and C. sobolifera are endowed with inhibitory effects on Lewis lung cancer, and the former one is superior to the latter.