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目的探讨血清抑制素A联合孕酮在预测早期先兆流产妊娠结局中的应用价值。方法 6~12周孕妇244例,根据妊娠结局分为正常妊娠组144例,先兆流产组60例,难免流产组40例。采用微粒子化学发光的方法检测血清抑制素A、孕酮水平。结果难免流产组抑制素A、孕酮水平明显低于其他两组,差异有统计学意义(P<0.05)。孕周相同时,难免流产组抑制素A、孕酮水平明显低于其他两组,差异有统计学意义(P<0.05);血清抑制素A联合孕酮预测早期先兆流产的敏感性、特异性及准确性分别为81.1%、80.6%、79.9%。结论血清抑制素A联合孕酮可显著提高对孕早期先兆流产结局预测的准确率。
Objective To investigate the value of serum inhibin A combined with progesterone in predicting the outcome of early threatened abortion. Methods 244 pregnant women of 6-12 weeks were divided into normal pregnancy group (144 cases), threatened abortion group (60 cases) and inevitable abortion group (40 cases). Serum inhibin A and progesterone levels were detected by microparticle chemiluminescence. Results inevitable abortion group inhibin A, progesterone levels were significantly lower than the other two groups, the difference was statistically significant (P <0.05). The same gestational age, inevitable abortion group inhibin A, progesterone levels were significantly lower than the other two groups, the difference was statistically significant (P <0.05); serum inhibin A combined with progesterone prediction of early threatened abortion sensitivity, specificity And the accuracy is 81.1%, 80.6%, 79.9% respectively. Conclusion Serum inhibin A combined with progesterone can significantly improve the prognosis of threatened abortion in early pregnancy prediction accuracy.