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治疗上颌骨肉瘤相当困难,因肿瘤的形态学变异较多、诊断较晚和病变范围较广,往往不宜手术。单独放疗效果较差,作者用区域性动脉内化疗结合放疗取得了较好疗效。于1970~1978年共治疗15例,男9,女6,年龄20~50岁。其中14例未进行特殊治疗,1例行综合治疗后3月复发。13例已有广泛性骨质破坏,9例扩展到眶部,6例扩展到鼻咽部。组织学诊断:血管肉瘤6例,网状内皮肉瘤4例,软骨肉瘤、神经原性肉瘤、多形细胞肉瘤、横纹肌肉瘤和浆细胞瘤各1例。全部病例都用γ-射线远距照射,按肿瘤生
The treatment of maxillary sarcoma is very difficult, because the morphological variation of the tumor is more, the diagnosis is later, and the lesion is wider. It is often not suitable for surgery. The effect of radiotherapy alone was poor, and the authors achieved good results with regional intra-arterial chemotherapy combined with radiotherapy. Between 1970 and 1978, 15 cases were treated with 9 males and 6 females, aged 20 to 50 years. Of these, 14 patients did not undergo special treatment, and 1 patient developed recurrence 3 months after comprehensive treatment. 13 cases had extensive bone destruction, 9 cases spread to the ankle, and 6 cases extended to the nasopharynx. Histologic diagnosis included 6 cases of angiosarcoma, 4 cases of reticuloendothelial sarcoma, 1 case of chondrosarcoma, neurogenic sarcoma, pleomorphic sarcoma, rhabdomyosarcoma, and plasmacytoma. All cases are irradiated with γ-rays, according to the tumor