细胞凋亡同肿瘤的发生、发展以及临床治疗关系密切。Survivin是凋亡抑制蛋白的一种,而p53是典型的抑癌基因,二者的表达异常可能是肿瘤发生、发展的重要因素。本研究应用DNA原位末端标记技术(Tunel)检测喉癌细胞凋亡指数(AI),免疫组织化学方法检测喉癌组织Survivin、p53蛋白的表 Apoptosis with the occurrence of tumor, development and clinical treatment are closely related. Survivin is a kind of apoptosis inhibitor protein, and p53 is a typical tumor suppressor gene. The abnormal expression of both may be an important factor in tumorigenesis and development. In this study, the apoptosis index (AI) of laryngeal carcinoma cells was detected by using Tunel, and the expression of Survivin and p53 protein in laryngeal carcinoma was detected by immunohistochemistry