补充铬对Ⅱ型糖尿病患者血糖和胰岛素变化的影响

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铬是正常糖代谢和脂代谢必需的营养物质。长期以来,人们认为铬与糖尿病的发病机制有关。然而,以前关于在非胰岛素依赖性糖尿病(NIDDM)患者补充铭来改善糖控制的效果的研究并没有得到相应的结果。本文作者在180例NID-DM患者中观察了补充铬对血糖控制的影响。将这180例患者随机地分成三组,一组为安慰剂组,一组每天补充两次,每次19.2μmol(1000μg)铬,一组每天补充两次,每次9.6μmol(500μg)铬。这些患者继续服用他们平时所用的药物,并且也不改变饮食和生活习惯。2个月以后,在每天接受19.2μmol(1000μg)铬的那组患者,HbAlc位明显改善,并且在4个月以后低于另一组补充铬的患者(安慰组HbAlc为8.5%±0.2%;9.6μmol铬组为75%±0.2%;19.2μmol铬组为6.6%±0.1%)。2和4个月以后19.2μmol组的空腹血葡萄糖也最低(4个月时的位:安慰组8.8±0.3mmol/L,19.2μmol铬组7.1±0.2mmol/L),并且该组的餐后2h血葡萄糖值也明显降低(4个月时的值;安慰组12.3±0.4mmol/L,19.2μmol格组10.5±0.2mmol/L)。在2和4个月后,在补充钻的两组中空腹和餐后2h血清胰岛素值明显降低,在每天刊、充19.2μmol铬的那组,4个月以后血浆总胆固醇也降低。这些结果表明补铬对巨型糖? Chromium is an essential nutrient for normal glucose metabolism and lipid metabolism. For a long time, people think chromium is related to the pathogenesis of diabetes. However, previous studies on the effect of glycemic control in patients with non-insulin-dependent diabetes mellitus (NIDDM) did not receive the same results. The authors examined the effect of chromium supplementation on glycemic control in 180 NID-DM patients. The 180 patients were randomized into three groups, one placebo group, one group supplemented with 19.2 μmol (1000 μg) chromium twice daily, one group supplemented with 9.6 μmol (500 μg) chromium . These patients continue to take their usual medications and do not change their diet and lifestyle habits. After 2 months, HbAlc was significantly improved in the group receiving 19.2 μmol (1000 μg) of chromium per day and was lower after 4 months in another group of patients chrome-supplemented (HbAlc in the placebo group 8.5% ± 0.2%; 9.6μmol chromium group 75% ± 0.2%; 19.2μmol chromium group 6.6% ± 0.1%). Fasting blood glucose was also lowest in the 19.2 μmol group after 2 and 4 months (at 4 months: 8.8 ± 0.3 mmol / L for the placebo group and 7.1 ± 0.2 mmol / L for the 19.2 μmol chromium group), and The 2 h postprandial blood glucose value was also significantly reduced (values ​​at 4 months; 12.3 ± 0.4 mmol / L in the placebo group and 10.5 ± 0.2 mmol / L in the 19.2 μmol group). After 2 and 4 months, there was a significant decrease in fasting and postprandial 2-h serum insulin values ​​in both groups of sham- peated drills and in the group with 19.2 μmol chrome per day, and total plasma cholesterol decreased after 4 months. These results suggest that chromium is added to the giant sugar?
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