我院近4年应用烟酸占替诺治疗急性重度一氧化碳中毒20例、一氧化碳中毒后迟发性脑病18例,与我院1993年～1998年收治的急性重度一氧化碳中毒16例、一氧化碳中毒后迟发性脑病14例作为对照组进行观察比较。临床资料病例选择:急性重度一氧化碳中毒患者36例均符合急性一氧化碳中毒的分类和临床诊断标准,一氧化碳中毒后迟发性脑病32例符合急性一氧化碳中毒迟 Nearly 4 years of our hospital niacin nicotinic acid treatment of acute severe carbon monoxide poisoning in 20 cases, 18 cases of delayed encephalopathy after carbon monoxide poisoning, and our hospital from 1993 to 1998 admitted to acute severe carbon monoxide poisoning in 16 cases, late carbon monoxide poisoning late 14 cases of encephalopathy as a control group were observed and compared. Clinical data Case selection: 36 patients with acute severe carbon monoxide poisoning are in line with the classification and clinical diagnostic criteria for acute carbon monoxide poisoning, delayed encephalopathy after carbon monoxide poisoning in line with 32 cases of acute carbon monoxide poisoning late