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原发性皮肤大细胞淋巴瘤(PCLCL)可分为T细胞性和B细胞性两类。T细胞表型PCLCL犤PCLCL(T)犦可以CD30阳性与否预期其预后。CD30+PCLCL(T)的预后较好。CD30-PCLCL(T)和CD30+非皮肤原发性LCL(T)的预后差。从蕈样肉芽肿转化成的CD30+皮肤LCL的预后一般差,从淋巴瘤样丘疹病演变成的CD30+-LCL仅系统性的预后差而皮肤CD30+-LCL的预后则不差。原发性皮肤多形T细胞性淋巴瘤、大细胞型和原发性皮肤T-免疫母细胞性淋巴瘤的预后差。B细胞表型原发性皮肤大细胞淋巴瘤中绝大多数为原发性皮肤滤泡中心细胞性淋巴瘤,其预后较淋巴结滤泡中心细胞性淋巴瘤为好。
Primary cutaneous large cell lymphoma (PCLCL) can be divided into two types of T cell and B cell. T cell phenotype PCLCL 犤 PCLCL (T) 犦 CD30 positive or not expected its prognosis. The prognosis of CD30 + PCLCL (T) is better. Poor prognosis for CD30-PCLCL (T) and CD30 + non-cutaneous primary LCL (T). The prognosis for CD30 + cutaneous LCL transformed from mycosis fungoides is generally poor, with CD30 + -LCL evolving from lympho-like papulosis as a mere systematic prognosis and a poor prognosis for cutaneous CD30 + -LCL. Poor prognosis of primary cutaneous T-cell lymphoma, large cell type, and primary cutaneous T-cell immunoblastic lymphoma. The majority of B cell phenotype primary cutaneous large cell lymphoma is primary cutaneous follicular central cell lymphoma whose prognosis is better than that of lymph node follicular central cell lymphoma.