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目的筛选薏苡仁提取物镇痛的活性部位。方法采用小鼠热板法、甩尾法和醋酸扭体法评价薏苡仁醇提物的4个不同极性部位的镇痛作用,筛选其镇痛有效部位。结果薏苡仁提取物的4个不同极性部位均有不同程度地镇痛作用,其中以石油醚部位和乙酸乙酯部位效果显著。结论薏苡仁提取物具有镇痛作用,其活性成分主要在石油醚和乙酸乙酯部位。
Objective To screen the active site of Analgesia of Coix Seed Extract. Methods The analgesic effect of four different polar sites of alcoholic extract of Coix lachryma - jobi was evaluated by mouse hot plate method, tail flick method and acetic acid writhing method, and the effective site of analgesia was screened. Results Coix seed extract four different polarity sites have varying degrees of analgesic effect, which parts of the petroleum ether and ethyl acetate site significant effect. Conclusion Coix seed extract has analgesic effect and its active ingredient mainly in petroleum ether and ethyl acetate.