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杀虫剂轮用和混用是当前害虫抗药性治理中最常采用的两种用药策略。该文用抗性模型和室内试验对轮用和混用延缓害虫抗性演化的效果及轮用最佳间隔期问题作了研究。模型模拟结果表明,在延缓害虫抗性演化方面轮用和混用对抗性演化的影响主要取决于杀虫剂作用强度、抗性基因型个体的适合度大小和杀虫剂混用后的毒理效应类型。两种杀虫剂轮用时,轮用间隔期以1(即两种杀虫剂隔次施用)为佳。以模型昆虫小菜蛾Plutellaxylostella在室内试验结果表明,氰戊菊酯单用(I)及与杀虫单轮用(II)和混用(1∶1)(III)连续处理8代后,抗性个体频率为001的小菜蛾种群其3龄幼虫对氰戊菊酯的抗性分别上升了7587(I)、2867(II)和5872(III)倍,与模型模拟结果表现出较好的一致性。据此,作者认为抗性模型可用于预测害虫抗性演化和评价抗性治理策略。
Pesticide rotation and mixing are the two most commonly used strategies for drug resistance in pest management. The resistance model and laboratory experiments were used to study the effect of rounding and mixing on the resistance evolution of pests and the optimal interval of rotation. The results of model simulations showed that the effect of the rotation and the confrontation evolution on pest resistance evolution depend on the intensity of insecticide, the suitability of individuals with resistant genotypes, and the type of toxicological effects after the pesticide mixture . When two insecticides are used rounds, the rounding interval is preferably 1 (ie, two insecticides are applied at intervals). The laboratory test of the model Plutella xylostella showed that after 8 generations of fenvalerate alone (I) and the combination with insecticidal single wheel (II) and a mixture of (1: 1) (III) The resistance of the third instar larvae to fenvalerate at the frequency of 001 was 7587 (I), 2867 (II) and 5872 (III) times higher than that of the model simulations respectively. Accordingly, the authors believe that the resistance model can be used to predict the evolution of pest resistance and to evaluate resistance management strategies.