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为评价激素治疗是否会对儿童心肌炎的病程产生影响,作者观察了连续13例经心肌活检证实的婴儿及儿童心肌炎患者,男8例,女5例。年龄1.1～14.8岁,平均为5.7±4.8岁。所有病人均有充血性心力衰竭,也有ST-T段改变,胸片提示心脏增大及肺水肿。超声心动图显示:5例心包积液,8例二尖瓣反流。平均左室射血分数为34±12％。全部病人使用强的松;1例加用硫唑嘌呤。有1例死亡。所有存活的病人均显示临床状况的改善,心电图、心脏大小及收缩功能恢复正常。无明显副作用。有8例重复心肌
To assess whether hormonal therapy may have an impact on the course of childhood myocarditis, the authors observed a series of 13 infants and children with myocarditis confirmed by cardiac biopsy, including 8 males and 5 females. Age 1.1 ~ 14.8 years old, with an average of 5.7 ± 4.8 years old. All patients had congestive heart failure, but also ST-T segment changes, chest X-ray showed that the heart and pulmonary edema. Echocardiography showed 5 cases of pericardial effusion and 8 cases of mitral regurgitation. The mean left ventricular ejection fraction was 34 ± 12%. All patients used prednisone; 1 case plus azathioprine. One patient died. All surviving patients showed clinical improvement, ECG, heart size and contractile function returned to normal. No obvious side effects. There are 8 cases of repeated myocardium