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目的探讨老年高血压病患者血压昼夜节律与动态动脉硬化指数的关系。方法根据动态血压检测结果将112例老年高血压病患者分为杓形组(n=37)、非杓形组(n=45)和反杓形组(n=30),并测定及计算动态动脉硬化指数(AASI)。结果3组年龄,体质量指数,总胆固醇、三酰甘油、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇、空腹血糖、病程和全天及白天平均收缩压、舒张压和脉压比较均无显著性差异。3组夜间平均收缩压、夜间平均舒张压、AASI比较有显著性差异(P<0.01)。结论动态血压昼夜节律的改变与动态动脉硬化指数相关。
Objective To investigate the relationship between circadian rhythm of blood pressure and dynamic arteriosclerosis index in elderly patients with essential hypertension. Methods According to the results of ambulatory blood pressure test, 112 cases of elderly patients with essential hypertension were divided into two groups: the dipper group (n = 37), non-dipper group (n = 45) and anti-dipper group (n = 30) Arteriosclerosis index (AASI). Results The age, body mass index, total cholesterol, triglyceride, low density lipoprotein cholesterol, high density lipoprotein cholesterol, fasting blood glucose, duration of disease, mean systolic blood pressure, diastolic blood pressure and pulse pressure were not significantly different among the three groups Sex differences. Mean nighttime systolic blood pressure, nighttime mean diastolic blood pressure, AASI were significantly different (P <0.01). Conclusion The changes of circadian rhythm of ambulatory blood pressure are related to the dynamic arteriosclerosis index.