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作者等曾报道食管癌高发区山西阳城县81 388户中,本病患者的家族集聚性,发病的代数分布及其血缘家族史资料,并阐述其遗传背景与防治措施。调查中还发现患者的一级亲属,尤以同胞之间常有同期罹患,甚至死亡年龄十分接近。本文通过死于本病的死亡年龄分析,探讨其遗传因素,供高发区防治工作参考。资料来源与分析从全县81 388户调查所得6 665食管癌阳性户中,同胞间同患该病者共为1 182户、736人(未计死亡年龄不详的兄弟同患者12户、27人,兄妹同患者28户、65人)。统计其
The authors have reported 81 families and 388 households in the high incidence area of esophageal cancer in Shanxi Yangcheng County, the patient’s family agglomeration, the incidence of the algebraic distribution and family history of ancestral data, and describes its genetic background and prevention measures. The investigation also found that the first-degree relatives of the patients, especially the siblings, often had the same period of time, and even the death age was very close. This article analyzes the death age of the disease and explores its genetic factors for reference in prevention and control of high-incidence areas. Data Sources and Analysis Among the 6,665 esophageal cancer positive households surveyed by 81,388 households in the county, there were 1,182 siblings and 736 people with siblings. The unexplained brothers with unknown age were 12 patients with 27 patients. , brothers and sisters with 28 patients, 65 people). Statistics