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目的:监测探讨本院Ⅰ类切口手术围术期抗菌药物临床应用及术后切口感染发生情况。方法:前瞻性统计分析2014年1—12月本院出院的全部Ⅰ类切口手术病人,对其完整资料进行统计分析。结果:2014年共有Ⅰ类切口手术2 161例,其中应用抗菌药物383例,抗菌药物预防使用率为17.72%;其中术前0.5~2 h应用350例,术前0.5~2 h用药率为91.38%;24 h内停药286例,24 h停药率为74.67%;预防用药最多的是头孢呋辛283例,占73.89%,其次为克林霉素78例,占20.37%;术后发生切口感染6例,感染率为0.28%。结论:目前本院Ⅰ类切口手术围术期抗菌药物使用基本达到国家抗菌药物治理目标,Ⅰ类切口手术术后切口感染率控制在0.5%以下,虽然抗菌药物使用率较低,但切口感染发生率并没有上升。虽然围手术期抗菌药物临床应用各项监测指标已达到国家的要求,但应用中仍然存在预防用药指征掌握不严、预防用药给药时机不妥、选药不当、给药方式不当、24h停药率低等问题亟待进一步规范。
OBJECTIVE: To monitor the clinical application of perioperative antimicrobial agents and the incidence of postoperative incision infection in Class Ⅰ incision in our hospital. Methods: Prospective statistical analysis was performed on all type Ⅰ incision patients discharged from our hospital from January to December 2014, and their complete data were analyzed statistically. Results: A total of 2 161 incision operations were performed in 2014, of which 383 were antibacterials and 17.72% were antibacterials. Among them, 350 were used 0.5-2 h before surgery and 91.38 0.5-2 h before surgery %; 286 cases were discontinued in 24 hours, 74.67% in 24 hours; 283 cases of cefuroxime were the most frequently used prophylaxis, accounting for 73.89%, followed by clindamycin in 78 cases (20.37%); postoperative occurred Incision infection in 6 cases, the infection rate was 0.28%. CONCLUSION: At present, the use of antimicrobial agents in type Ⅰ Ⅰ incision in our hospital basically meets the national goal of antimicrobial treatment. The incision infection rate of type Ⅰ incision is controlled below 0.5%. Although the use of antibacterials is low, incisional wound infection occurs Rate did not rise. Although perioperative monitoring indicators of clinical application of antimicrobial drugs have reached the national requirements, but there are still indications for prevention of abuse in the application laxity, improper timing of drug delivery, improper drug selection, improper drug delivery, 24h stop Low drug rates and other issues need further specification.