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动物实验和人体研究表明摄入大量脂肪与癌症的发生及死亡有关。脂肪可能是通过抑制免疫系统对肿瘤的监视而促进肿瘤的发生。自然杀伤细胞在免疫监视肿瘤中起重要作用。本次研究旨在观察膳食脂肪摄入量对人体自然杀伤细胞活性的影响。受试者是26名健康男性,年龄为31±5.5岁((?)±SD),体重在理想体重±10％范围以内,不吸烟,无过敏体质。先是进行1.5～2个月的基线调查,让受试者熟悉低脂肪膳食计划(脂肪热比<30％)和膳食调查方法(24小时回忆+4日记录法)。随后是3个月的膳食干预
Animal experiments and human studies have shown that the intake of large amounts of fat is associated with the onset and death of cancer. Fat may promote tumor formation by inhibiting the immune system’s surveillance of tumors. Natural killer cells play an important role in immune surveillance of tumors. The aim of this study was to investigate the effect of dietary fat intake on the activity of natural killer cells in humans. Subjects were 26 healthy males, aged 31 ± 5.5 years (± SD) and were within ± 10% of their ideal body weight. They were non-smoker and had no allergies. First, a baseline survey of 1.5 to 2 months was conducted to familiarize participants with the low-fat diet (fat-to-fat ratio <30%) and dietary survey methods (24-hour recall + 4-day recording). Followed by 3 months of dietary intervention