Wetlands in the Jianghan Plain are important components of wetland types in lake area in the middle and lower reaches the Changjiang (Yangtze) River and they fulfill many uses and functions related to hydrology,waste assimilation, ecosystem productivity and biodiversity. Owing to natural factors and human activities, especially excessive reclamation from lakes, the shrinking process of the lakes has been accelerated. Wetland ecosystem has shown the characteristics of vulnerability. According to the analysis of wetland ecological function in the Jianghan Plain, this paper presented an index system related to productivity, stability and environmental capacity. By using the method of Analytic Hierarchy Process, we computed the values of the relative weights of the indexes, and evaluated the vulnerability level of the wetland ecosystem by the method of multi-indexes. The case study showed that the fragile extent of wetland ecosystem in the Jianghan Plain is 5.6. This means that the wetland ecosystem in the Jiang-han Plain is laid to the state of middle vulnerability. Therefore, the wetland conservation and eco-rehabilitation in the Jianghan Plain should be paid attention to.