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瑞典药物副作用委员会在1966至1970五年期间收集了药物诱发溶血性贫血共45例,其中男性7例(16%),女性38例(84%),女病例占明显优势。发病率逐年似有增加,而以年龄大者发病率较高,55岁以上的有28例。引起溶血性贫血的药物,以甲基多巴最多,计21例(47%),其中2例死亡。其次为磺胺制剂(10例),砜类(3例)。其他药物包括呋哺坦丁、保泰松、肼苯哒嗪、颠茄、麦角胺、非那西汀、水杨酸等。
The Swedish Drug Side Effects Committee collected 45 cases of drug-induced hemolytic anemia during the five-year period from 1966 to 1970, of which 7 (16%) were male and 38 (84%) were female, with predominantly female cases. Incidence increases year after year, while the incidence of older persons is higher, 55 cases over the age of 28 cases. Drugs that cause hemolytic anemia, the most methyldopa, accounting for 21 cases (47%), of which 2 died. Followed by sulfonamide preparations (10 cases), sulfones (3 cases). Other drugs include furosemide, phenylbutazone, hydralazine, belladonna, ergotamine, phenacetin, salicylic acid and the like.