“健体宁”是用中药配制的新型运动饮料。能提高运动员的速度、耐力、改善竞技状态、增强身体素质,本文通过口服和静脉注射两种途径对该饮料的安全性与作用机制进行了实验研究,结果如下: 一、选用40只小白鼠作半数致死量测定,求得LD_(50)=127.1±0.027g/kg,提示本品无毒性影响。二、选用47只大白鼠作最大耐受量测定,求得其最大耐受量为成人用量的222.5倍,显示本品有较大安全性。三、选用25只小白鼠作亚急性毒性试验后,心、肝、脾、肺、肾、脑等脏器的病检,均属阴性。四、选用18只家兔所作的心缩力、血压、呼吸、尿量等机能观察中,未发现不良影响。五、选用20只小白鼠作游泳耐力试验,服药组游泳持续时间明显延长。(P<0.001) 动物实验表明:运动饮料“健体宁”。安全性大,对正常机能无干扰,可以捉高耐力。 “Jian Ti Ning” is a new type of sports drink formulated with traditional Chinese medicine. It can improve the athlete’s speed, endurance, improve the competitive state, and enhance the physical quality. This article through the oral and intravenous injection of the beverage safety and mechanism of action conducted an experimental study, the results are as follows: First, select 40 mice used as The median lethal dose was determined to obtain LD 50 = 127.1 ± 0.027 g/kg, indicating that the product has no toxic effects. Second, 47 rats were selected for maximum tolerance measurement, and the maximum tolerated dose was 222.5 times that of adults, indicating that the product has greater safety. 3. After 25 mice were selected for subacute toxicity test, the examinations of organs such as heart, liver, spleen, lung, kidney, and brain were all negative. Fourth, the use of 18 rabbits in the performance of systolic, blood pressure, respiration, urine, etc., observed no adverse effects. 5. Twenty mice were used for swimming endurance test. The duration of swimming in the medication group was significantly prolonged. (P<0.001) Animal experiments showed that: sports drinks “healthy body”. Great safety, no interference with normal function, can catch high endurance.