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[目的]探讨胃神经鞘瘤的临床病理特征及诊治方法。[方法]回顾性分析南京医科大学附属苏州医院2000年1月至2016年12月期间收治并经病理证实的8例胃神经鞘瘤患者的临床资料。[结果]临床主要表现为上腹部胀痛、返酸(8例)、腹部包块(3例)、上消化道出血伴休克(1例)和解黑便(4例)。术前腹部增强CT、超声胃镜、上消化道造影(UGI)均提示胃部实质性不定性肿块。8例均行手术治疗,术前无一例确诊,术后均行病理学检查确诊,其中恶性1例(术后生存16个月),良性7例(预后均较好)。[结论]胃神经鞘瘤无特异性临床表现,术前确诊率低,误诊率高,常通过病理组织学检查可确诊,一经确诊,应及早行手术治疗。
[Objective] To investigate the clinicopathological features and diagnosis and treatment of gastric schwannoma. [Methods] The clinical data of 8 patients with gastric schwannoma admitted to Suzhou Hospital Affiliated to Nanjing Medical University from January 2000 to December 2016 were retrospectively analyzed. [Results] The main clinical manifestations of upper abdomen pain, acid reflux (8 cases), abdominal mass (3 cases), upper gastrointestinal bleeding with shock (1 case) and solution melena (4 cases). Preoperative abdominal enhanced CT, endoscopic ultrasonography, upper gastrointestinal imaging (UGI) were prompted qualitative gastric qualitative lumps. Eight patients underwent surgical treatment. None of them were diagnosed preoperatively, and pathologically confirmed postoperatively. Among them, 1 was malignant (16 months postoperatively) and 7 benign (all with good prognosis). [Conclusion] Gastric schwannoma have no specific clinical manifestations. Preoperative diagnosis rate is low, misdiagnosis rate is high, often diagnosed by histopathological examination, once diagnosed, surgical treatment should be carried out as soon as possible.