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美国能源部所属的阿贡国家实验室同摩托罗拉公司、帕卡德仪器公司以及俄国科学家最近决定联合开发生物芯片。 据该实验室出版的《前沿》杂志报道,作为美国人类基因组工程的一个组成部分,这种芯片测定人类基因组序列的速度可望比目前使用的方法快数千倍。 生物芯片采用的是一种“微型胶体”技术。这种微型胶体如同一个装有化学试剂的微型试管,遇到不同的化学物质会产生不变的变化,探测这些变化就可推断出遇到的化学物质的成分。按照设计,研究人员将把多达数万个微型胶体堆放在玻璃片上制成生物芯片。当用它测试基因序列时,基因上不同的化学成分就会导致芯片各部位产生不同的变化。根据这一变化就能推断这一基因的化学结构,从而破译这一基因。这种生物芯片每秒能够进行数千次生物反应,在几秒之内就能破译一个原因。
The Argonne National Laboratory affiliated with the U.S. Department of Energy has recently decided to jointly develop biochips with Motorola, Packard Instruments and Russian scientists. According to the lab’s Frontiers magazine, as part of the U.S. human genome project, the chip is capable of measuring human genome sequences thousands of times faster than currently used methods. Biochip uses a “micro-colloid” technology. Like a microtube filled with chemical reagents, the microcolloid is subject to constant changes in different chemicals, and the detection of these changes leads to the inference of the chemical composition encountered. By design, researchers will deposit as many as tens of thousands of micro-colloids on glass to make bio-chips. When using it to test the gene sequence, different chemical components of the gene lead to different changes in each part of the chip. According to this change can deduce the chemical structure of the gene, thus deciphering this gene. This biochip can perform thousands of biological reactions per second, deciphering a single cause in seconds.