干扰素α-2b可用于多发性骨髓瘤等恶性肿瘤的维持治疗。虽然该药对肾脏的毒副作用很少,但常引起中等量蛋白尿。本文报告一例应用重组干扰素α-2b治疗引起的急性肾功能衰竭。患者,女性,49岁,因恶心呕吐,尿量减少入院。两年前曾确诊为IgG-k型多发性骨髓 Interferon α-2b can be used in the maintenance of multiple myeloma and other malignancies. Although the drug on the kidneys little side effects, but often cause moderate proteinuria. This article reports an example of acute renal failure caused by treatment with recombinant interferon alpha-2b. The patient, female, 49 years old, was hospitalized for reduced nausea and vomiting. Two years ago was diagnosed as IgG-k type of multiple bone marrow