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乙型肝炎表面抗原(HBsAg)曾在唾液、精液、乳汁、胆汁、肠腔积液、腹水、尿及粪内检出,但据我们所知,尚未在脑脊液里发现。现报告在1例黑人小孩的脑脊液内检出 HBsAg。女孩6岁,1980年5月18日因发热1周住院。无黄疸史。表现嗜睡,无黄疸。肝肿大,无触痛,无慢性肝病的体征。入院后4天,患儿有失语,在全身抽搐后进入昏迷。临床诊断为病毒性脑病。血含 HBsAg,效价1:8,000。以后再检查,其血及脑脊液 HBsAg 均呈阳
Hepatitis B surface antigen (HBsAg) has been detected in saliva, semen, milk, bile, intestinal fluid, ascites, urine and feces but to the best of our knowledge has not been found in cerebrospinal fluid. HBsAg is now reported in the cerebrospinal fluid of one black child. Girl 6 years old, May 18, 1980 hospitalized for 1 week due to fever. No history of jaundice. Performance drowsiness, no jaundice. Hepatomegaly, no tenderness, no signs of chronic liver disease. 4 days after admission, children with aphasia, convulsions in the body into a coma. Clinical diagnosis of viral encephalopathy. Blood contains HBsAg, titer 1: 8,000. After checking, the blood and cerebrospinal fluid HBsAg were positive