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本文着重对1984年1月~1984年22月期间,辅以维生素B_6与东莨菪碱治疗新生儿破伤风68例。本法既能达到神经传递的抑制,又能阻断乙酰胆碱与受体的结合。经临床观察疗效较满意,疗程5~7天,少数7~14天。治疗组:治愈46例,好转8例,治愈好转率为79.4%;死亡14例,病死率为20.59%,纠正病死率为11.76%。对照组:77例,治愈40例,好转11例,治愈好转率为66.23%;死亡26例,病死率为33.76%,纠正病死率为28.57%。从两组相比结果说明,本组治愈好转率明显升高,病死率明显下降。
This article focuses on the January 1984 ~ 1984 in 22 months, supplemented with vitamin B_6 and scopolamine treatment of 68 cases of neonatal tetanus. This method can not only achieve the inhibition of neurotransmission, but also block the combination of acetylcholine and receptor. The clinical observation of more satisfactory treatment, treatment of 5 to 7 days, a few 7 to 14 days. In the treatment group, 46 cases were cured and 8 cases improved. The healing improvement rate was 79.4%, 14 cases died, the case fatality rate was 20.59%, and the corrected case fatality rate was 11.76%. In the control group, 77 cases were cured, 40 cases were cured and 11 cases improved. The healing improvement rate was 66.23%, 26 cases died, the case fatality rate was 33.76% and the corrected case fatality rate was 28.57%. Comparing results from the two groups shows that the cure rate improved significantly, the mortality rate decreased significantly.