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目的:分析小儿穿孔性阑尾炎致病菌群的变化特点及其对抗菌药物敏感性与临床使用因素,为临床正确使用抗菌药物提供参考。方法:选取2014年1月—2015年12月间收治的小儿穿孔性阑尾炎患者50例(男35例,女15例),分析小儿穿孔性阑尾炎的致病菌群变化、耐药性特点及其对抗菌药物使用的关系。结果:小儿穿孔性阑尾炎的致病菌主要是大肠埃希菌和铜绿假单胞菌,其他致病菌有肺炎克雷伯菌、土生克雷伯菌、流感嗜血杆菌、屎肠球菌、醋酸钙不动杆菌、弗劳地枸橼酸细菌等,感染致病菌的种类与患者术后住院时间、抗菌药物使用无紧密联系。结论:导致小儿穿孔性阑尾炎的致病菌谱变化不明显,术中脓液经微生物培养其结果准确判断致病菌种类,有助于术后合理选用抗菌药物。
OBJECTIVE: To analyze the characteristics of pathogenic bacteria in children with perforated appendicitis and its sensitivity to antibiotics and clinical factors, so as to provide a reference for the correct use of antibiotics in clinic. Methods: Fifty patients (35 males and 15 females) with perforation appendicitis admitted to our hospital from January 2014 to December 2015 were enrolled in this study. The changes of pathogenic bacteria in children with perforation appendicitis and their drug resistance The use of antibacterial drugs. Results: Pathogenic bacteria in children with perforation appendicitis were Escherichia coli and Pseudomonas aeruginosa. Other pathogens were Klebsiella pneumoniae, Klebsiella pneumoniae, Haemophilus influenzae, Enterococcus faecium, acetic acid Acinetobacter, Florian citrate bacteria, etc., the type of pathogenic bacteria infected with patients after hospitalization, the use of antibacterials are not closely linked. Conclusion: There is no obvious change of pathogenetic spectrum in children with perforation appendicitis. The intraoperative pus culture by microbiological culture can accurately determine the pathogen species and help to choose the appropriate antimicrobial agents after operation.