炎症是人类疾病中最常见且复杂的病理过程,有大量炎症介质参与其中[1]。炎症部位的细胞因子、趋化因子的持续存在和由其引发的级联反应能够诱导细胞增殖,趋化炎症细胞聚集,增加活性氧产物的产生,导致DNA氧化损伤。有DNA损伤或发生了基因突变的增殖细胞在富含炎症细胞和多种生物 Inflammation is the most common and complex pathological process in human diseases, with a large number of inflammatory mediators involved [1]. The persistent presence of cytokines and chemokines at the site of inflammation and cascade reactions initiated by them can induce cell proliferation, chemotactic inflammatory cell aggregation, increase production of reactive oxygen species, and DNA oxidative damage. Proliferating cells with DNA damage or mutations are rich in inflammatory cells and many organisms