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目的对比丹参酮ⅡA与硝酸甘油治疗冠心病不稳定型心绞痛的临床效果。方法 80例冠心病不稳定型心绞痛患者在应用辛伐他汀、地西泮、卡托普利、倍他乐克的基础上,随机分为A组(n=40例):静脉注射丹参酮ⅡA40mg/d:B组(n=40例):静脉注射硝酸甘油10～20mg/d。治疗20min后对比患者症状的改善,心电图ST段的恢复情况。对比观察其药物副作用。结果丹参酮ⅡA组较硝酸甘油组症状均有明显改善,心电图ST段均有所恢复,两组之间(P<0.05),但丹参酮ⅡA组药物不良反应小。
Objective To compare the clinical effects of tanshinone Ⅱ A and nitroglycerin in the treatment of unstable angina pectoris. Methods Eighty patients with unstable angina pectoris were randomly divided into group A (n = 40) on the basis of simvastatin, diazepam, captopril and metoprolol: intravenous injection of tanshinone Ⅱ A40mg / d: Group B (n = 40): intravenous nitroglycerin 10 ~ 20mg / d. After 20 minutes of treatment, the improvement of symptoms and the recovery of ST segment of ECG were compared. Contrast to observe the side effects of the drug. Results The symptoms of tanshinone Ⅱ A group were significantly improved compared with those of nitroglycerin group. The ST segment of electrocardiogram was recovered in both groups (P <0.05). However, the tanshinone ⅡA group had less side effects.