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目的 了解功能性与无功能性胰岛细胞肿瘤在临床病理特征方面存在的差异。方法 将 4 4例胰岛细胞肿瘤分为功能组和无功能组 ,对其临床病理特征进行回顾性分析比较。结果 功能组 3 6例 ,无功能组 8例。无功能组病程短 ,定位诊断阳性率高 ,肿瘤体积大 ,多位于全胰或胰头部 ,可合并浸润或转移 ,手术操作复杂 ,切除率较低 ,治愈率较低 ,生存期较短。两组镜下细胞形态相似。结论 无功能性胰岛细胞肿瘤治疗较困难 ,预后较差。
Objective To understand the differences in clinicopathological features between functional and nonfunctioning islet cell tumors. Methods Forty-four cases of pancreatic islet cell tumors were divided into functional group and non-functional group. Their clinical pathological features were retrospectively analyzed and compared. Results There were 36 patients in functional group and 8 patients in no functional group. In the non-functional group, the disease duration is short, the positive rate of localization diagnosis is high, and the tumor volume is large. Most of them are located in pancreatic or pancreatic head, which can be combined with infiltration or metastasis. The operation is complicated, the resection rate is lower, the cure rate is lower, and the survival period is shorter. The morphology of the cells in both groups was similar. Conclusion Nonfunctional islet cell tumor therapy is difficult and its prognosis is poor.