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中枢神经系统炎症反应是多种中枢神经系统病变的重要病理特征,包括神经退行性疾病(阿尔茨海默病、帕金森病及亨廷顿病等)、抑郁症、术后认知功能障碍、精神分裂症等[1-4]。相对分子质量18 000转位分子蛋白(translocator protein,TSPO)是一个有5个跨膜区的疏水性蛋白,由于其可与苯二氮结合,最初被称为外周型苯二氮受体(peripheral type benzodiazepine receptor,PBR
Central nervous system inflammatory response is an important pathological feature of various central nervous system diseases including neurodegenerative diseases (Alzheimer’s disease, Parkinson’s disease and Huntington’s disease, etc.), depression, postoperative cognitive dysfunction, schizophrenia Disease [1-4]. Relative molecular weight 18 000 Translocator protein (TSPO) is a hydrophobic protein with five transmembrane domains. Since it binds to benzodiazepine, it was originally called the peripheral type benzodiazepine receptor type benzodiazepine receptor, PBR