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目的评价９９Ｔｃｍ甲氧基异丁基异腈（ＭＩＢＩ）显像在诊断乳腺癌腋窝转移淋巴结中的价值。方法１８例病理检查证实的乳腺癌病人，术前均行９９ＴｃｍＭＩＢＩ显像。１４例乳腺未触及肿块者作为对照组。静脉注射９９ＴｃｍＭＩＢＩ１１１０ＭＢｑ后５，３０和６０ｍｉｎ进行早期及延迟显像，分别于左侧位、右侧位和前后位进行观察。患者均在显像后１周内进行手术治疗，腋窝淋巴结清扫后行病理检查。结果１８例腋窝淋巴结转移者显像阳性为１１例，敏感性７８６％，乳腺癌腋窝转移淋巴结显像与淋巴结大小及转移癌细胞侵犯程度有密切的关系。结论９９ＴｃｍＭＩＢＩ乳腺癌腋窝转移淋巴结显像在鉴别良恶性肿瘤、估计预后以及制订手术方案中均有较重要的临床意义
Objective To evaluate the value of 99Tcm methoxyisobutylisonitrile (MIBI) imaging in diagnosing axillary metastatic lymph nodes of breast cancer. Methods Eighteen patients with breast cancer confirmed by pathological examination underwent 99Tcm-MIBI imaging before operation. Fourteen patients with untouched breast masses served as controls. Early and delayed imaging were performed at 5, 30, and 60 min after intravenous injection of 99Tcm-MIBI1110MBq, and were observed on the left, right, and anterior and posterior positions, respectively. All patients underwent surgical treatment within 1 week after imaging. Pathological examination was performed after axillary lymph node dissection. Results There were 11 cases with positive axillary lymph node metastasis in 11 cases, and the sensitivity was 78.6%. The axillary lymph node metastasis of breast cancer was closely related to the size of lymph nodes and the extent of metastatic cancer cells. Conclusion 99TcmMIBI breast cancer axillary metastatic lymph node imaging has important clinical significance in differentiating benign and malignant tumors, estimating prognosis, and making surgical plans.