石英引起的肺纤维化病变,伴随着脂质代谢的紊乱,脂质含量增加,肺磷脂积聚是矽肺的重要标志。近年研究证明,矽肺发病过程和自由基反应有关,实验动物和矽肺病人脂质过氧化物(LPO)含量提高,但对磷脂和LPO的关系报道不多,本文观察矽肺大鼠血磷脂和LPO水平的动态,探讨两者的关系,为研究矽肺发病机理提供依据。 Pulmonary fibrosis caused by quartz lesions, accompanied by disorders of lipid metabolism, lipid content increased, pulmonary alveolar accumulation of silicosis is an important symbol. In recent years, studies have shown that the pathogenesis of silicosis and free radical reactions, experimental animals and patients with silicosis increased lipid peroxide (LPO), but the relationship between phospholipids and LPO little reported in this paper, the observation of silicosis rats LPO and LPO levels To explore the relationship between the two, provide the basis for studying the pathogenesis of silicosis.