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目的探讨静脉免疫球蛋白(IVIG)在预防早产儿感染、提高早产儿成活率中的作用。方法77例早产儿随机分成两组,治疗38例,在常规治疗基础上加用IVIG400mg/kg静脉滴注,隔日1次,视经济状况连用1～2次;对照组39例,仅常规治疗,不使用IVIG治疗。结果两组早产儿住院一周后采用静脉血检测C反应蛋白,结果比较有统计学差异,P<0.05。结论IVIG预防早产儿感染,提高成活率疗效显著,值得临床推广。
Objective To investigate the role of intravenous immunoglobulin (IVIG) in preventing premature infant infection and improving the survival rate of premature infants. Methods 77 premature infants were randomly divided into two groups, 38 cases were treated with intravenous infusion of IVIG 400mg / kg on the basis of conventional treatment, once every other day, depending on the economic status of 1 or 2 times; control group of 39 patients, only routine treatment, Do not use IVIG treatment. Results One week after hospitalization in both groups, venous blood samples were taken for the detection of C-reactive protein. The results were statistically significant (P <0.05). Conclusion IVIG is effective in preventing infection and improving survival rate in premature infants, which is worthy of clinical promotion.