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生物学家一直认为氧对需氧生物完全有益,Mccord氏和Fridovich氏发现清除超氧化物自由基的超氧化物歧化酶(SOD)后,氧的有毒作用逐渐被人们认识。肺脏是气体交换组织与氧代谢有密切关系,特别在慢性阻塞性肺部疾患有肺功能障碍时,出现组织缺氧、缺血时其氧代谢过程中自由基变化情况如
Biologists have always believed that oxygen is entirely beneficial to aerobic organisms. Mccord’s and Fridovich’s discovery of the toxic effects of oxygen after scavenging superoxide radical superoxide dismutase (SOD) has been gradually recognized. Lung is a gas exchange organization and oxygen metabolism are closely related, especially in chronic obstructive pulmonary disease with pulmonary dysfunction, tissue hypoxia, ischemia during oxygen metabolism during free radical changes such as