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对 4 0例丙型肝炎患者的血清 AL T、抗 - HCV及 HCVRNA进行了检测。结果显示 :在急慢性丙型肝炎中 ,抗 - HCV阳性率分别为 83.3%、93.8% ,HCVRNA阳性率分别为 50 %、6 8.8% ,有 4例抗 - HCV阴性急性患者 HCVRNA阳性。抗 - HCV阳性者中有 51.4 % HCVRNA阳性。HCVRNA的检出在 AL T异常情况下较正常明显高 (P<0 .0 5)。提示 HCVRNA早期诊断意义较抗 - HCV大 ,抗 - HCV在一定程度上能反映 HCVRNA的情况 ,而 AL T高低亦可间接反映 HCV的复制状态。
Serum ALT, anti - HCV and HCVRNA in 40 hepatitis C patients were detected. The results showed that the positive rates of anti-HCV in acute and chronic hepatitis C were 83.3% and 93.8% respectively, and the positive rates of HCVRNA were 50% and 68.8%, respectively. HCV RNA was positive in 4 anti-HCV negative acute patients. 51.4% of HCV RNA positive in anti-HCV positive. The detection of HCV RNA was significantly higher than normal in patients with abnormal ALT (P <0.05). The results suggest that the early diagnosis of HCV RNA is more important than anti-HCV, anti-HCV can reflect the condition of HCVRNA to some extent, and the level of ALT indirectly reflects the replication status of HCV.