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Hepatoblastoma is the most common malignant hepatic tumor in children. About 50% of the cases occur before the age of 18 months and almost all before the age of 2 years. We present an extremely rare case of hepatoblastoma in an 11-year-old girl, which was pathologically verified and treated twice with transcatheter arterial infusion combined with radical resection. To date she has been followed-up for 15 years and has shown normal development after the operation. She has received no chemotherapy or radiation and has displayed no evidence of metastatic or recurrent disease.