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目的探讨冠心病患者血清中同型半胱氨酸与血脂水平的关系。方法分别测定79例冠心病(CHD)患者和30例正常对照组血清同型半胱氨酸(HCY)及血脂水平,并进行比较及相关性分析。结果 CHD组血清HCY、甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)均明显高于正常对照组。而CHD组HCY水平与载脂蛋白a(Lp(a)具有相关性。结论 HCY是CHD的一个独立因素。HCY水平与Lp(a)两者联合检测有助于CHD患者的诊断与防治。
Objective To investigate the relationship between serum homocysteine and blood lipids in patients with coronary heart disease. Methods Serum levels of homocysteine (HCY) and lipids were measured in 79 patients with coronary heart disease (CHD) and 30 normal controls respectively, and compared and analyzed. Results The levels of serum HCY, TG, TC, HDL-C and LDL-C in CHD group were significantly higher than those in normal control group. However, HCY level in CHD group was correlated with Lp (a) .Conclusion HCY is an independent factor of CHD.The combination ofHCY level and Lp (a) is helpful for the diagnosis and prevention of CHD.