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微核是细胞在有丝分裂时因各种有害因素损伤，使细胞核成份残留在核外的微小核染色质块。其作为评价药物、放射线及细胞毒性物质对人、动物及体外细胞损伤已有较长的历史。为了解最新相关的研究情况，我们就最近国外有关细胞微核的形成机理、特性及临床实用价值等综述如下。１
Micronucleus is a kind of tiny nuclear chromatin mass that remains in the nucleus when the mitotic cells are damaged by various harmful factors during mitosis. It has a long history of evaluating human, animal and in vitro cell injury as a drug, radioactive, and cytotoxic agent. In order to understand the latest relevant research, we summarize the recent formation mechanism, characteristics and clinical practical value of cellular micronuclei in foreign countries. 1